Farebrother J, Rohner F

February 2018 – The Biology of the First 1,000 days

Iodine deficiency used to be highly prevalent in many parts of the world until salt iodization programs and other prevention strategies were implemented and scaled up, beginning in the 1980s in most countries. Great progress toward reducing iodine deficiency and its consequences has been achieved since; however, large numbers of people continue to be affected. This chapter examines mechanisms of iodine, thyroid hormones, and growth during the “1,000-day window”, the period between conception and when a child is 2 years of age.

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